All submitted manuscript should contain original research that has not been published previously and is not under consi-deration for publication elsewhere.

Manuscript submission

Manuscripts can be submitted online or by mail.
Online submission: For instructions, visit:
http://www.e-emm.org
Submission by mail: Submit three print copies of each manuscript including one original set with high quality gra-phics along with a Manuscript submission form (available at http: //www.e-emm.org/ or on page ix). A letter must be included indicating the address, telephone and fax numbers, and E-mail address of the corresponding author. Send manuscripts and correspondence to:

Submission of digital files: Following acceptance of a manu-script, authors should submit a diskette containing the final version of the manuscript. Microsoft Word is preferred, although other formats are generally acceptable. It is also encouraged to submit digital files of figures prepared in appropriate formats (see Tables and Figures). If authors do not provide electronic files of their figures, they will be charged separately (about US$5.00 for a simple line graph) and publication of the manu-script will be delayed. The label on the diskette, CD, or ZIP should indicate the journal name, manuscript number, and corresponding author's name.
Manuscript and other materials will not be returned unless specifically requested.

Organization of the manuscript

Manuscripts must be typed or printed on 2 1× 29.7 cm (A4 size) high-quality paper in double spacing throughout with at least 3 cm wide margins on all sides. The text must be typed in a font size of at least ten points. The manuscript is to be ar-ranged in the following order: ( a ) title, author(s), and com-plete address(es) of institution(s); ( b ) abbreviations; ( c ) running title; ( d ) abstract and keywords; ( e ) introduction; ( f ) materials and methods; ( g ) results; ( h ) discussion; ( i ) acknowledgements; ( j ) references; ( k ) figure legends; ( l ) tables; and ( m ) figures. Num-ber all pages with the title page as page 1. To make papers more readable and informative, the EMM requests that authors mark the followings for typesetting in italic.

Title: The title of the manuscript should be as short and informative as possible. It should not contain nonstandard ab-breviations, subtitles, or colons, nor exceed two printed lines (about 18 words). The EMM reserves the right to reword titles, with the final approval of the authors. The title page should also give the names of all authors and their complete mailing addresses. The title page should also include the name, the telephone and fax numbers, and the E-mail address of the author to whom all correspondence about the manuscript, in-cluding proofs, will be sent.

Abbreviations: Standard abbreviations may be used without definition. Any nonstandard abbreviations should be spelled out on first use, followed by the abbreviated form in parentheses. Thereafter, abbreviated form may be used throughout the manu-script. Undefined abbreviations cannot be used. Provide a list of all nonstandard abbreviations in alphabetical order on a page following the title page.

Running title: The running title to be printed at the top of each page of a published paper cannot exceed 6 words.

Abstract: The abstract should succinctly and clearly describe the major findings reported in the manuscript. It must not exceed 250 words nor contain nonstandard or undefined abbreviations or specialized terms. It should be understandable in itself, since it is frequently used as an abstract in indexes.

Keywords: Six keywords should be appended to the abstract in alphabetical order. The keywords should be standard MeSH- Medline terms (http://www.nlm.nih.gov/mesh). The list submitted may be amended to ensure that entries are MeSH-Medline terms.

Introduction: The introduction should present the purpose of the studies reported and their relationship to earlier work in the field. It should not be an extensive review of the literature nor, in general, exceed two typed pages.

Materials and Methods: The Materials and Methods should be as brief as possible but sufficiently complete to permit a qualified reader to repeat the experiments reported. Only truly new procedures should be described in detail; previously pub-lished procedures should be cited in references. Modifications of previously published procedures need to be given in detail only when this is necessary to repeat the work.

Results: The results of experiments should be presented in figures and tables, although some results that do not require documentation can be given solely in the text. Extensive dis-cussion should not be given in the Results section.

Discussion: The Discussion should be concise (usually less than four typed pages) and focused on the interpretation of the results rather than a repetition of the Results section.
Notes added in proof can be added to a manuscript only with the consent of the Editor.
Errors in a published paper should be corrected in the EMM in "Additions and Corrections."

References: The references must be cited by Harvard sys-tem (author and date) not the numbering system. References should be quoted in the text with the author's name and date in parentheses, and listed at the end of the paper in alpha- betical order. Journal names are abbreviated according to Pub-Med (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=journals). Authors are fully responsible for the accuracy of the references. "Personal communication" or "unpublished data" should be written in the text in parenthesis but not listed in references. Refer-ences for journals and books should be in the following styles:

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